The protein encoded by Hsp70 gene is an important member of the heat shock protein family. Hsp70 Proteins are central components of the cellular network of molecular chaperones and folding catalysts. They assist a large variety of protein folding processes in the cell by transient association of their substrate binding domain with short hydrophobic peptide segments within their substrate proteins. The substrate binding and release cycle is driven by the switching of Hsp70 between the low-affinity ATP bound state and the high-affinity ADP bound state. Thus, ATP binding and hydrolysis are essential in vitro and in vivo for the chaperone activity of Hsp70 proteins.

This Abmart monoclonal antibody is produced by immunizing mice with a polypeptide (Abmart SEAL mAb technology) corresponding to heat shock cognate 70 kDa protein.

Heat shock cognate 70 kDa protein

XP_007207158.1

68 kDa heat shock protein; dnaK-type molecular chaperone HSP70-1; epididymis secretory protein Li 103; Heat shock 70 kDa protein 1; heat shock 70 kDa protein 1/2; Heat shock 70 kDa protein 1A; heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1B; Heat shock 70 kDa protein 2; Heat shock 70 kDa protein 3; heat shock 70kD protein 1A; heat shock 70kDa protein 1A; heat shock protein 70-1; heat shock protein, 70 kDa 3; heat shock-induced protein; heat shock-induced protein, Hspa70; Hsp68; HSP70-1; HSP70-1/HSP70-2; HSP70-1A; HSP70-2; HSP70.1/2; HSP70.1/HSP70.2; HSP70.3; HSP70I; HSP72; HSPA1; inducible heat shock protein 70

Western blotting                           1:1000-1:5000

69

Store at -20°C, stable for one year from the date of shipment.

Cherry

Mouse IgG