Catalog No: CY5366 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC ICC/IF IP FC
UniProt ID: Q92934
All Names: BAD; BBC6; BCL2L8; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter; Bcl2-antagonist of cell death;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 23 kDa
WB: 1:1000~1:2000
IHC: 1:50~1:200
ICC/IF: 1:50~1:200
IP: 1:30
Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L),but not that of Bcl-2 (By similarity). Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Western blot analysis of BAD expression in Hela cell lysate.