Catalog No: CY6906 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC
UniProt ID: O60238
All Names: Adenovirus E1B19k binding protein B5; BCL2/adenovirus E1B 19 kd protein interacting protein 3a; BNIP3a; BNIP3H; BNIP3L; BNIP3L protein; NIP3 like protein X; NIP3L; NIX;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 35 kDa
WB 1:500~1:2000
IHC 1:50~1:200
Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. May function as a tumor  suppressor. Inhibits apoptosis induced by BNIP3.

Western blot analysis of BNIP3L expression in K562 cell
lysate.