Catalog No: CY5743 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC
UniProt ID: P46937
All Names: 65 kDa Yes associated protein; YAP; YAp 1; YAP2; YAP 65;YKI; Yorkie homolog;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 65 kDa
WB 1:5000~1:20000
IHC 1:50~1:200
YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.

Western blot analysis of Phospho-YAP1 (S127)
expression in (1) HeLa cell lysate; (2) HeLa cell lysate
treated with FBS+calyculin A.