Catalog No: CY5592 Reactivity: Human
Isotype: Rabbit IgG Applications: WB IHC
UniProt ID: Q16790
All Names: MN; P54/58N; CAIX; CA9; Carbonic anhydrase IX; CAH9;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 50 kDa
WB: 1:500~1:2000
IHC: 1:50~1:200
CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. Reversible hydration of carbon dioxide.Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia. Tissue specificity: Expressed primarily in carcinomacells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in  the epithelial cells of gastric mucosa.

Western blot analysis of CA9 expression in Human stomach lysate.