Catalog No: CY6709 Reactivity: Human
Isotype: Rabbit IgG Applications: WB IHC ICC/IF
UniProt ID: P06731
All Names: adhesion molecule 5; CD66e; Ceacam5; Meconium antigen 100;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 180-220 kDa
WB 1:500~1:2000
IHC 1:50~1:200
ICC/IF 1:50~1:200
Carcinoembryonic antigen (CEA), also known as CD66e or CEACAM5, is a 180-200 kDa cell surface glycoprotein whose expression is elevated in intestinal carcinomas and other tumors. CEA mediates cell adhesion, though little more is known about its biological activity. Expression of CEA is correlated with tumerogenicity, and it has been shown to play a role in cell migration, adhesion and invasion in culture cells,as well as in metastasis in vivo.

Western blot analysis of CEA(CD66e) expression in human colon cancer lysate.