Catalog No: CY5814 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC ICC/IF FC
UniProt ID: P51149
All Names: CMT2B; PRO2706; PSN; RAB7, member RAS oncogene family; RAB7A; RAB7A, member RAS
oncogene family; Ras associated protein RAB7; Ras related protein Rab7a;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 23 kDa
WB 1:1000~1:2000
IHC 1:50~1:200
ICC/IF 1:50~1:200
FC 1:50
Plays a role in the fusion of phagosomes with lysosomes. Plays important roles in microbial pathogen infection and survival, as well as in participating in the life cycle of viruses. Microbial pathogens possess survival strategies governed by RAB7A, sometimes by employing RAB7A function (e.g. Salmonella) and sometimes by excluding RAB7A function.

Western blot analysis of RAB7 expression in (1) A375 cell lysate; (2) 3T3 cell lysate.