The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.?

 

KIAA0661, RBP95, STARING

 

Mouse IgG

 

113.6kDa

 

Human

 

This Abmart monoclonal antibody is produced by immunizing mice with a sythetic peptide(KLH coupled)corresponding to amino-terminal residues of human BRE1B

 

Store at -20°C, stable for one year from the date of shipment.

 

Western blotting        1:1000-1:5000                     
Immunoprecipitation     10 tests                
FACS                    1:100-1:200