Catalog No: CY6596 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB FC
UniProt ID: P01100
All Names: activator protein 1; AP-1; C-FOS; cellular oncogene c-fos; Cellular oncogene fos; FOS; G0/G1 switch regulatory protein 7; G0S7;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 62 kDa
WB 1:500~1:2000
FC 1:50
Fos a proto-oncogenic transcription factor of the bZIP family. Dimerizes with proteins of the JUN family,thereby forming the transcription factor complex AP-1. FOS proteins function as regulators of cell proliferation,differentiation, and transformation. In some cases, expression of FOS has also been associated with apoptotic cell death. Expression increases upon a variety of stimuli, including growth factors, cytokines,neurotransmitters, polypeptide hormones, stress and cell injury.

Western blot analysis of c-Fos expression in HeLa cell lysate treated with TPA.