Catalog No: CY7009 Reactivity: Human
Isotype: Rabbit IgG Applications: WB IHC
UniProt ID: P08174
All Names: Cd55a; Complement decay accelerating factor; CROM; DAF; Daf-GPI; Daf1; GPI-DAF;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 55-80kDa
WB 1:1000~1:5000
IHC 1:50~1:200
This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cellassociated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

Western blot analysis of CD55 expression in A549 cell lysate.