Catalog No: CY5849 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB ICC/IF
UniProt ID: P60484
All Names: Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase
PTEN; Mutated in multiple advanced cancers 1; Phosphatase and tensin homolog; PTEN; MMAC1; TEP1;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 54 kDa
WB 1:1000~1:2000
ICC/IF 1:50~1:200
PTEN (phosphatase and tensin homologue deleted on chromosome ten), also referred to as MMAC (mutated in multiple advanced cancers) phosphatase, is a tumor suppressor implicated in a wide variety of human cancers. PTEN regulates p53 protein levels and activity (8) and is involved in G protein-coupled signaling during chemotaxis.

Western blot analysis of Phospho-PTEN (S380)
expression in (1) MCF-7 cell treated with alkaline
phosphatase lysate; (2) MCF-7 cell lysate.