Catalog No: CY6567 Reactivity: Human, Mouse, Rat
Isotype: Rabbit IgG Applications: WB, IHC, ICC
UniProt ID: P49840
All Names: DKFZp686D0638; glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 51,46kDa
WB: 1:500~1:2000
IHC: 1:50~1:200
ICC: 1:50~1:200
GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

Western blot analysis of GSK3 alpha/ beta
phosphorylation expression in 293 cell lysate treated
with AP.