Catalog No: CY5274 Reactivity: Human, Mouse, Rat
Isotype: Rabbit IgG Applications: WB IHC ICC IP
UniProt ID: P49023
All Names: Paired box protein Pax-1; PAX-1; PAXI; paxillin; paxillin alpha;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: Synthesized peptide
Molecular Wt.: 60kDa
WB: 1:500~1:1000
IHC: 1:50~1:100
ICC: 1:50~1:100
IP: 1:50
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix(focal adhesion). PXN is a multi-domain cytoskeletal protein that localizes primarily to focal adhesion sites to the extracellular matrix. Phosphorylated by focal adhesion kinase (FAK) and is a component of integrin signaling. Its phosphorylation provides docking sites for recruitment of signaling molecules to focal adhesions.

Western blot analysis of extracts from HeLa cells, using
Paxillin antibody.