Catalog No: CY5427 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC ICC IP FC
UniProt ID: P19320
All Names: VCAM1; L1CAM; VCAM 1; V CAM 1; DKFZp779G2333; CD106;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 100 kDa
WB: 1:500~1:2000
IHC: 1:50~1:200
ICC: 1:50~1:200
IP: 1:20
This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis.Two alternatively spliced transcripts encoding different isoforms have been described for this gene.Tissue specificity: Expressed on inflamed vascular endothelium, as well as on macrophage-like and dendritic cell types in both normal and inflamed tissue.INVITROGEN: CD106 is expressed on bone marrow stromal cells,myeloid cells, and endothelial cells.

Western blot analysis of VCAM1 expression in Mouse
kidney lysate.