Catalog No: CY5205 Reactivity: Human Rat
Isotype: Rabbit IgG Applications: WB IHC ICC/IF FC
UniProt ID: P14780
All Names: MMP9; GELB; CLG4B; Matrix Metalloproteinase 9; MANDP2; Gelatinase beta;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 78 kDa
WB: 1:500~1:2000
IHC: 1:50~1:200
ICC/IF: 1:50~1:200
MMP9 May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration.Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments.Degrades fibronectin but not laminin or Pz-peptide. Belongs to the peptidase M10A family. Activated by 4-aminophenylmercuric acetate and phorbol ester. Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.

Western blot analysis of MMP9 expression in (1)Rat
kidney tissue lysate;(2)Rat lung tissue lysate.