Catalog No: CY5496 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC ICC/IF FC
UniProt ID: P0DMV8
All Names: HSP72; HSPA1; HSP70I; HSP70-1; HSP70-1A; HSPA1A;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 70 kDa
WB: 1:500~1:2000
IHC: 1:100~1:500
ICC/IF: 1:50~1:100
FC: 1:100
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Western blot analysis of HSP70 expression in (1) K562
cell lysate; (2) 293T cell lysate.