Catalog No: CY7126 Reactivity: Human
Isotype: Rabbit IgG Applications: WB IHC ICC IP FC
UniProt ID: Q13158
All Names: FADD protein; MORT1;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 28kDa
WB 1:500~1:2000
IHC 1:50~1:200
ICC/IF 1:50~1:200
IP 1:50
FC 1:50
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8
proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.

Western blot analysis of USP31 expression in A431 cell
lysate.