Catalog No: CY5914 Reactivity: Human
Isotype: Rabbit IgG Applications: WB ICC/IF
UniProt ID: P56524
All Names: Histone deacetylase 4; HD4; HDAC4; AHO3; BDMR;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 140 kDa
WB 1:1000~1:2000
ICC/IF 1:50~1:200
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in
transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the
formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte
enhancer factors such as MEF2A, MEF2C and MEF2D.

Western blot analysis of HDAC4 expression in Hela
lysate.