Catalog No: CY6909 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC
UniProt ID: Q676U5
All Names: APG16 like 1; APG16L; APG16L beta; ATG16 autophagy related 16 like 1; ATG16A; ATG16L;
Atg16l1; Autophagy related protein 16 1; IBD10; WD repeat domain 30; WDR30;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 68 kDa
WB 1:500~1:2000
IHC 1:50~1:200
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membranebound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Western blot analysis of Atg16L1 expression in HeLa cell lysate.