Catalog No: CY5306 Reactivity: Human Mouse Rat
Isotype: Rabbit IgG Applications: WB IHC ICC/IF IP FC
UniProt ID: P42345
All Names: FRAP; FRAP1; FRAP2; RAFT1; Rapamycin target protein; kinase mTOR;
Form: Liquid
Storage instructions: Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage buffer: pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity: Affinity-chromatography
Immunogen: A synthesized peptide
Molecular Wt.: 289 kDa
WB: 1:500~1:1000
IHC: 1:50~1:100
ICC/IF: 1:50~1:100
An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis
regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle
arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

Western blot analysis of mTOR expression in Jurkat cell lysate.